Tube optics vs reflex

I have discovered if I want to see the target I have to shoot a red dot. I have several 45's with Holosun, and they are fine.
I just got a Marvel 22 conversion, and put an Ultra dot 6 on it.  I am becoming a fan, not to mention a really good trigger on the 45.  
I think the Ultradot must ride the slide in 45 mode?  seems like a lot of metal recoiling fast would not be good for the  tube mounts, etc.  I would not be a fan of mounting a lot of crap on the side of the pistol to hold the tube/dot-not pretty.
Ok, do the tube/dots hold up?  This is BE only.

I had a slide mounted ultradot6 on my 45, with zero issues. I run 9000s now for improved glass. I have a frame mount 45 that has an ultradot, have not had any issues.

Short answer is yes, they hold up on a slide mount setup.
I've shot over 90,000 rounds of 45 wadcutter through several wad guns. With one exception at Perry in 2002 (a failed tension spring that Larry Carter fixed within the hour), they've performed very well.

Tube dot 100%!!

Weigand makes a good frame mount. It is gunsmith (or skilled machinist) installed, as it requires drilling and tapping several holes in the relatively thin dust cover. There are other frame mount options. We frame mount bullseye shooters are a minority, but we are fervent in our belief they are superior. 

Reflex red dots are not common. The disadvantages are coarse adjustment, backlash and most of them don't have clicks, so sighting in can be frustrating.

The tube is also good for us as it encourages us to have the dot near the center (less parallax error) and to develop good recovery because if the gun is out of alignment when you come back on target the dot will be gone.

Tube optic or reflex, they both have similar accuracy potential.  Tube have slightly better optical properties but those are lost in pistol shooting.  These are two examples. One with a tube the other with a reflex.  I chose the reflex for the 745 because I didn’t want to drill the slide and the dovetails can’t take the reciprocating mass.